If you've been spending time in Path of Exile 2's endgame, Sacrosanctum is probably one of those uniques you keep hearing about in chat. It's tied to a lot of builds, but it's not the sort of item you just trip over on your way through the acts. It sits in the global drop pool, so yes, it can come from almost anything in a high-level zone, from a random chest to a dead trash mob. That said, you...
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